Morpholine

    • Product Name: Morpholine
    • Chemical Name (IUPAC): Oxazinane
    • CAS No.: 110-91-8
    • Chemical Formula: C4H9NO
    • Form/Physical State: Liquid
    • Factroy Site: No.89 Lihua street, Funing District, Qinhuangdao City, Hebei Province, China
    • Price Inquiry: sales2@boxa-chem.com
    • Manufacturer: Qinhuangdao Lihua Starch
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    Specifications

    HS Code

    641031

    Chemicalname Morpholine
    Molecularformula C4H9NO
    Molarmass 87.12 g/mol
    Casnumber 110-91-8
    Appearance Colorless liquid
    Odor Ammonia-like odor
    Boilingpoint 128°C
    Meltingpoint -5°C
    Density 1.00 g/cm³
    Solubilityinwater Miscible
    Ph Approximately 10.5 (1% solution)
    Vaporpressure 11 mmHg at 25°C
    Flashpoint 35°C (closed cup)
    Autoignitiontemperature 295°C
    Refractiveindex 1.454

    As an accredited Morpholine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Morpholine is typically packaged in 200-liter blue HDPE drums with hazard labels, manufacturer's details, and batch number clearly indicated.
    Container Loading (20′ FCL) 20′ FCL for Morpholine typically loads 16–18 metric tons, packed in steel drums or ISO tanks, ensuring safe, secure transport.
    Shipping Morpholine should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled as hazardous. It must be transported according to regulations for flammable and toxic substances, typically under UN2054. The chemical should be kept away from heat, sparks, and incompatible materials, with proper ventilation and emergency procedures readily accessible during shipping.
    Storage Morpholine should be stored in a tightly closed container in a cool, dry, well-ventilated area away from heat, sparks, open flames, and incompatible substances such as acids, oxidizers, and CO₂. It should be protected from moisture and direct sunlight. Storage areas must be equipped with spill containment and clearly labeled. Use corrosion-resistant containers and keep away from unauthorized personnel.
    Shelf Life Morpholine typically has a shelf life of 2 years when stored in tightly closed containers, away from heat, moisture, and direct sunlight.
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    Certification & Compliance
    More Introduction

    Morpholine: Practical Experience from the Production Floor

    What Sets Our Morpholine Apart

    As a chemical manufacturer with years of morpholine production under our belt, we know the real backbone of this versatile amine lies in experience—not just formulas and data sheets. Commercial customers often need more than a product; they need a reliable supply that runs pure, cuts waste, and fits with tight production schedules. Over the years, we’ve seen how the small details make the difference. Morpholine isn’t just a raw material, nor is it simply another amine among many. Its blend of volatility, water solubility, and amine character opens doors where other compounds fall short. From batch to batch, consistency matters. In our operations, we focus on strict control—no titles, no cut corners.

    Key Features and Real-World Uses

    Every drum of morpholine leaving our facility comes with a spec that’s been earned—not guessed. Our typical product meets a purity standard over 99.5%, with water content held below 0.5%. This level doesn’t just wind up on paper; it shows in feedback from steam system engineers and pharmaceutical formulation groups. Customers depend on the amine’s unique profile: boiling point of around 129°C, miscible in water, a faintly fishy smell that always tells you what’s in the tank.

    In application, morpholine’s role covers a lot of ground. Refineries rely on its corrosion inhibition—an engineer once explained how a leaky steam line cost days of downtime until our product stabilized the pH. In rubber chemical processing, morpholine acts as a solid accelerator. Textile plants use it to improve dye uptake, with operators favoring it over competing amines thanks to cleaner results and simpler effluent treatment. Pharmaceutical syntheses often call for morpholine’s reliability as a building block; a clean batch here can mean the difference between regulatory approval and a lost production run. We hear from formulators that off-ratio or contaminated amines require full line shutdowns. It pays to get the product right from the start.

    Comparing Morpholine With Other Amines and Solvents

    Customers sometimes weigh the merits of morpholine against common alternatives like piperazine, triethanolamine, or diethanolamine. On the plant floor, these look similar at first glance. Anyone loading a reactor knows that morpholine’s narrow boiling range and full water miscibility are hard to substitute, especially in closed loops. Staff have tried alternatives, but report sludging, uncontrollable foaming, or excessive system wear over time. Morpholine resists carbon steel corrosion better in high-pressure boiler water—one of those advantages that gets lost in a spec sheet, but stands out in ten-year maintenance records.

    Other producers focus on maximizing apparent capacity, but we’ve learned that under-controlled amine streams build impurities, especially under strong alkaline or acidic process steps. Morpholine offers reliable performance with minimal cross-reaction, and that’s a big deal if your process specifies minimal by-product formation. Customers with experience in formulating metalworking fluids report smoother operations and longer service life for system components. Some environments need alternatives for toxicity or regulatory reasons; we openly discuss these scenarios with our clients and help devise approaches that ensure continuity without risking compliance or safety.

    Production Philosophy and Quality Commitment

    Manufacturing morpholine demands more than just a good reactor and a distillation column. We learned early on that process stability defines product quality. Starting with carefully chosen diethylene glycol and ammonia, we control our batch parameters so each run matches the last. Operators monitor reaction progress with in-process checks, ready to intercept deviations before they carry downstream. This vigilance means our output meets the promised purity time after time. The maintenance crew calibrates analytical equipment daily—one missed check can mean off-spec tanks. Some try to chase higher yields at the expense of cleanup or waste streams, but this leads to problems in both quality and compliance.

    Steam system users count on us to keep out chloride and sulfate carry-over. Pharmacy-grade customers demand even tighter control over secondary amine residues and trace organics. We maintain dedicated production lines and validated cleaning programs for these distinct demands. That experience translates beyond compliance—it means fewer customer complaints and more production time saved for everyone in the chain.

    Lessons Learned in Real Industry Settings

    Over the years, our teams have worked out practical solutions to recurring hurdles. Bulk morpholine shipping, for instance, tends to invite moisture contamination in humid climates. We equip our drums and bulk containers with custom liners and nitrogen-blanketed atmospheres to minimize uptake. Customers asked for this after batches arrived out-of-spec more than once using third-party logistics. Now, with track-and-trace shipment integration, users can anticipate exact arrival and tank farm allocation, shaving days off transition time. We also found that routine tank inspection at the customer site—sometimes dismissed as “not my problem” by others—can catch leaks or legacy contamination that could spoil an entire charge. Some issues are best caught before they start the pump.

    Our involvement doesn’t stop at shipping. When a customer faced unexpected pitting corrosion in a high-pressure steam loop, we sent technical specialists to their site. Tracking the problem back to subtle water quality shifts saved them from unplanned shutdowns. Actions like these cement trust and ensure production lines keep moving. Other clients use morpholine in high-purity API syntheses, where even low-level metal traces can halt a batch. Our investment in closed-system filling and full traceability isn’t simply a selling point—our teams have seen the cost of product recalls where QA falters.

    Navigating Regulations and Environmental Impact

    Factories everywhere face rising expectations for both product safety and environmental stewardship. Morpholine’s low acute toxicity sets it apart from some other amines, but regulatory frameworks can shift. We keep our eye on standards such as REACH, TSCA, and international labeling obligations. There’s no shortcut here. Auditors have told us they are seeing increasing focus on residual amines and N-nitrosamine impurities. We work with industry consortia to keep testing protocols current and stay transparent about both analytical methods and findings.

    Some customers operate in sensitive ecosystems, where water discharges and air emissions face local scrutiny. Our teams collaborate in designing handling and venting protocols. We’ve run joint workshops on reclaiming morpholine-laden wash water—recovering usable material and reducing wastewater loads alike. Investment in vapor capture isn’t wince-worthy if it keeps the site running year after year without neighbors filing complaints or local agencies pausing operations for reviews.

    Supporting Innovation and Cost Efficiency

    Morpholine isn’t just an ingredient; it’s a tool for unlocking new processes. Over time, we’ve worked with partners refining pipeline cleaning regimens or developing heat transfer fluids with tougher chemistry. Adapting product form—bulk liquid, high-purity or specialized blends—lets us support niche applications that don’t attract big headlines, but keep smaller operators competitive. One example came from a regional food packaging plant, which replaced a more hazardous process amine to reduce both risk and insurance costs, without disrupting flavor or regulatory compliance. The switch involved close coordination, but rewards came through reduced staff exposures and less challenging air handling.

    In multi-shift operations, customer maintenance leads found morpholine simplifies training and system upkeep—handling protocols stay consistent, and suppliers know what to expect from ordering through restocking. We’ve redesigned delivery schedules to work with tight production windows and avoid costly plant downtime. This responsiveness means plant managers can schedule crews and minimize overtime just to wait for chemicals that should have arrived yesterday.

    Continuous Improvement and Customer Partnership

    Our manufacturing teams gather feedback from the field, then feed what we learn back into process refinement. For example, we adopted a double-seal drum closure after clients reported accidental spillage in overseas shipments. These steps come from experience, not theory—we listen, adapt, and verify at every turn. Some customers suggested slight modifications to spec sheets for easier recordkeeping and regulatory submissions; we worked these suggestions in without extensive bureaucracy.

    Customer audits are not paperwork exercises—they reveal pressure points and opportunities. Open plant tours and on-site sampling have uncovered room for better batch segregation between high and standard purity morpholine. Improvements came at cost, but have dramatically reduced lot crossover incidents. Operators now flag irregularities early, instead of filling out post-hoc reports when a problem surfaces downstream.

    Challenges and Ways Forward

    Real-world morpholine manufacturing is about sweating the details. Impurities can sneak in from leaky valves, unclean reactor surfaces, or poorly controlled feedstock. We’ve had to overhaul sections of our plant after root-cause analysis found legacy line contamination. Addressing these on the fly prevented major recall events.

    There’s always pressure to cut corners, especially on energy, waste disposal, and logistics. We fight that urge by running small-scale trials before rolling out major process changes. In morpholine production, simple shortcuts almost always mean higher long-term costs in QC checks, batch failures, or environmental penalties.

    The market for morpholine will keep evolving. Tougher exposure limits may emerge, or customers might push for bio-based amines or lower-residue profiles. Our work bridging daily operations with R&D puts us in a good position to adapt. Operators and chemists share lessons constantly—whether on unexpected side reactions in pilot projects or ways to further minimize downtime during turnaround. Our experience teaches us that sustainable quality isn’t an endpoint; it’s a process.

    Working With Morpholine: From Our Plant to Yours

    Customers who’ve visited our facility quickly realize morpholine isn’t just another spec in a catalog. It holds a special place because it solves tricky problems other amines or solvents can’t match. Its combination of volatility, moderate base strength, and water compatibility opens up uses in places other chemicals foul or underperform. Whether it’s ensuring steam plant reliability, producing pharmaceuticals, or aiding in synthetic processes, our focus remains the same—deliver a product that does the job right, on time, and with no surprises lurking in the tank.

    Plenty of chemical producers move units; not everyone backs up their product with decades of hands-on troubleshooting, collaborative problem-solving, and honest communication. Morpholine deserves that kind of respect, because the cost of getting it wrong hits hard. We’ve built our systems and processes on what we’ve learned—not from slides or presentations, but from the experience forged in actual production, across industries and geographies. What sets us apart isn’t just our process or product, but our willingness to shoulder responsibility with every shipment, and to stand by every customer when the unexpected hits. That’s how we see morpholine—not just as a chemical, but as a commitment.